Mission Massimo Foundation

The Mission Massimo Foundation is a non-profit organisation that promotes the prevention, diagnosis and treatment of childhood Leukodystrophies. These are a group of life-threatening genetic conditions that affect the formation of myelin, a complex fatty substance that acts as an insulator around nerve fibres in the brain much like electrical wiring. Unfortunately, more then 50% of childhood Leukodystrophies remain genetically unclassified offering families little hope of treatment and a usually tragic outcome. Whilst individually rare, these disorders are not altogether uncommon. In fact they may affect up to 1 in 3,000 births yet their existence remains almost unknown. Our mission is to accelerate the discovery of genetic variations responsible for these disorders and to translate these finding into clinical treatments.